About Us

How Synapse First Got Started

Synapse Biomedical Inc. (SBI) was founded in September 2002 to commercialize the NeuRx® Diaphragm Pacing System (DPS) which has been developed during a twenty-year period, in collaboration with Case Western Reserve University and the University Hospitals of Cleveland. The innovative research performed at these institutions has led to significant advances in state-of-the-art electrical stimulation for the treatment of chronic respiratory insufficiency.

Utilizing the Power of the NeuRx DPS®

This innovation allows clinicians to reach beyond current methods of treatment to meet the ventilatory needs of people dependent on mechanical ventilation due to spinal cord injuries and to provide diaphragm conditioning for patients with ALS.

Our Culture

Our culture is best described by its people: smart, driven, energetic and committed to improve the lives of individuals with neurological impairment, such as spinal cord injury, Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig’s disease and others.

Our Mission

Synapse Biomedical (SBI) is dedicated to the research, development and commercialization of life-altering neurostimulation products. The pioneering of this technology will allow the global healthcare community to reach beyond current methods of treatment and provide a new standard of care to improve patient outcomes.

The Synapse Team

Anthony R. Ignagni

President & CEO

Anthony R. Ignagni is the President & CEO of Synapse Biomedical, as well as a co-founder. He brings to the company over twenty years of experience in the development and commercialization of neurostimulation medical devices. He received his Bachelors and Masters degrees in Biomedical Engineering from Case Western Reserve University and managed software development at the Cleveland FES Center for eleven years. As a founding member of NeuroControl Corp. and VP of New Product Development & Operations, he has brought neurostim devices to market in the US and Europe.

Moustapha Diop

Chief Operating Officer & Managing Director-Europe

Moustapha Diop joined Synapse Biomedical in 2005 as Chief Operating Officer. He has over 15 years of experience in the medical device industry and prior to Synapse Biomedical, he was the Director of Global Operations Planning for Invacare Corporation. Moustapha relocated to France as Director of European Operations with NeuroControl where his responsibilities also included management of sales and marketing in Northern Europe. He has his Bachelor degree in Physics from Oberlin College and Masters in Operations Management from Weatherhead School of Management (Case Western Reserve University).

Timothy Crish

V.P. of Product Development & Operations

Timothy Crish joined Synapse Biomedical in 2006 as V.P. of Product Development & Operations. He has over 20 years of experience in the medical device industry (implantables, circuitry & software). Over the years, he has held various engineering positions in product development at the Cleveland FES Center as well as at Axon Engineering, Picker International, Life Systems Inc., and Case Western Reserve University. He has a Bachelor of Science in Biomedical Engineering and a Masters of Science in Electrical Engineering from Case Western Reserve University.

Mike Fritz

Vice President, Clinical & Regulatory Affairs

Mike Fritz has 20 years of experience with medical device companies (Class III, implantable, PMA- and HDE-track devices) with roles in clinical operations, regulatory affairs, clinical data management, and engineering.  Mike worked for 14 years with larger companies (Guidant, Boston Scientific, and Medtronic) and, most recently, 6 years with start-ups (Cyberkinetics and Synapse Biomedical).  Mike has a MS in software engineering degree (University of St. Thomas) and a bachelor of electrical engineering (BEE) degree (University of Minnesota).