Kerwin AJ1, Yorkgitis BK2, Ebler DJ2, Madbak FG3, Hsu AT4, Crandall ML2. Author information Abstract Background: Cervical spinal cord injury (CSCI) is devastating. Respiratory failure, ventilator-associated pneumonia (VAP), sepsis, and death frequently occur. Case reports of diaphragm pacing system (DPS) have suggested earlier liberation from mechanical ventilation in acute CSCI... read more →
Nov
01
Sep
06
Onders RP1, Elmo M2, Kaplan C2, Schilz R3, Katirji B4, Tinkoff G2. Author information Abstract Background: Cervical spinal cord injury can result in catastrophic respiratory failure requiring mechanical ventilation with high morbidity, mortality, and cost. Diaphragm pacing was developed to replace/decrease mechanical ventilation. We report the largest long-term results in... read more →
Oct
15
With the support of a $3 million Ohio Third Frontier Innovation Platform Program grant, Synapse Biomedical Inc. will lead the commercialization of third generation neurostimulation technology pioneered by Professor Hunter Peckham and his team at Case Western Reserve University (CWRU). Synapse Biomedical has also brought in global partners to assist... read more →
Oct
13
The Post Approval Study’s (PAS) Interim Data Showed Device Safety and Median Survival Post-Implant of 20.9 months Synapse Biomedical Inc. reported today that the U.S. multi-center, Post Approval Study (PAS) studying the use of the NeuRx® Diaphragm Pacing System (DPS) in ALS is continuing to enroll patients. The Post Approval... read more →
Sep
21
Synapse Biomedical Inc. received word that the Northeast ALS Consortium (NEALS) Data and Safety Monitoring Board (DSMB) has recommended suspending new enrollment of the NEALS randomized control trial (RCT) of diaphragm pacing in patients with ALS. While there was no safety concern seen in the interim analysis, the decision is... read more →
Aug
25
Synapse Biomedical Inc. announced today that an abstract regarding Synapse Biomedical’s Post Approval Study (PAS), a multi-center, clinical trial to further demonstrate the diaphragm pacing system’s safety and survival benefit has been accepted for presentation at the 26th International Symposium on ALS/MND. The Post Approval Study (PAS) of diaphragm pacing... read more →
Aug
11
Analysis of Diaphragm Pacing in 214 Patients with Lou Gehrig’s Disease (ALS) Shows Safety and Improved Survival Benefit Synapse Biomedical Inc. announced today that an abstract regarding a decade of use of the NeuRx Diaphragm Pacing System® has been accepted for presentation at the 26th International Symposium on ALS/MND. A... read more →
Aug
07
Origent Data Sciences accurately predicts function and survival of patients using Diaphragm Pacing System Synapse Biomedical Inc. announced today that the abstract Analysis of Function and Survival in ALS Patients with Diaphragm Pacing using Virtual Controls by Origent Data Sciences, was accepted for presentation at the 26th International Symposium ALS/MND... read more →
Dec
17
This story first appeared in MPR News on December 17, 2013 This month marks the third year since Bruce Kramer of Minneapolis received a medical diagnosis that changed his life in an instant. Kramer, who was 54 at the time, had noticed his left foot feeling heavy and a little... read more →